CDC7 (cell division cycle 7)

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Molecular characterization of cell cycle gene CDC7 from Saccharomyces cerevisiae.

The product of the CDC7 gene of Saccharomyces cerevisiae appears to have multiple roles in cellular physiology. It is required for the initiation of mitotic DNA synthesis. While it is not required for the initiation of meiotic DNA replication, it is necessary for genetic recombination during meiosis and for the formation of ascospores. It has also been implicated in an error-prone DNA repair pa...

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Regulation of Saccharomyces cerevisiae CDC7 function during the cell cycle.

The yeast Cdc7 function is required for the G1/S transition and is dependent on passage through START, a point controlled by the Cdc28/cdc2/p34 protein kinase. CDC7 encodes a protein kinase activity, and we now show that this kinase activity varies in the cell cycle but that protein levels appear to remain constant. We present several lines of evidence that periodic activation of CDC7 kinase is...

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Cell cycle, cell division, and cell death

Hilary A. Collera,b,* and Arshad Desaic,d aDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095; bDepartment of Biological Chemistry, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095; cDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093; dLudwig Cancer Research Cente...

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Chromatin Structure and the Cell Division Cycle

Measurements of actinomycin-(3)H binding in synchronized HeLa cells reveal that the binding capacity of chromatin decreases progressively during the S phase despite a doubling of nuclear DNA content, reaches a minimal level during G(2) and mitosis, and then increases gradually throughout the subsequent G(1) interval. Since this pattern was evident in experiments with living cells, ethanol-fixed...

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Effect of water stress on cell division and cell-division-cycle 2-like cell-cycle kinase activity in wheat leaves

In wheat (Triticum aestivum) seedlings subjected to a mild water stress (water potential of -0.3 MPa), the leaf-elongation rate was reduced by one-half and the mitotic activity of mesophyll cells was reduced to 42% of well-watered controls within 1 d. There was also a reduction in the length of the zone of mesophyll cell division to within 4 mm from the base compared with 8 mm in control leaves...

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ژورنال

عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology

سال: 2020

ISSN: 1768-3262

DOI: 10.4267/2042/70816